these antiplatelets help a little bit w/ overall risk reduction after a heart attack, I'd say, but the big game changer would be a clot buster like an injectable version of alteplase/tenecteplase or something like that. The caveat is that the better it is at reversing clots, the higher risk of hemorrhage; alteplase/tenecteplase is typically given in a critical care/emergency Dept setting w/ surgery/intensivists hovering over the patient...
You will almost certainly never see at home versions of these drugs, the risk profile is far too great. Roughly 13% of strokes are hemorrhagic and that's just the first and most obvious hazard.
If I remember correctly, part of the goal here is to gain a bit of time while the patient gets to the ER. I’m no expert but as you seem to have alluded to, the risk profile of alteplase/tenecteplase doesn’t seem to be well suited to an autoinjector with “if in doubt, use it and call the ambulance” instructions.
yeah but then it'll have to compete w/ aspirin/clopidogrel...meaning they're limited on the margins they can set for the med, and injectables tend to be pricey...
